FDA Moves to Reevaluate Several Peptides American Med Spa Association Why Are People Injecting Themselves with Peptides? The New Yorker Peptides Lack Reliable Safety Information, Watchdog Warns Some peptides are FDA approved drugs. Some are legal supplements. Some are neither. The same word, peptide, covers all three categories. The regulatory status of the specific compound is what determines legality. Gray Market Peptides: So Much Hype, So Little Data