Glutathione concentration in BSO treated, BSO and NAC co treated, NAC Download Scientific Diagram 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for The Depletion of Nuclear Glutathione Impairs Cell Proliferation in 3t3 Fibroblasts PLOS One Exploring the Lean Phenotype of Glutathione Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles PLOS One The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis American Journal of Physiology Gastrointestinal and Liver Physiology American Physiological Society