6 health benefits of glutathione HMP Shunt Biochemistry Medbullets Step 1 Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification Item Scheme showing the enzymatic reactions that catalyze the pyruvate dehydrogenase complex, including pyruvate dehydrogenase activity and diaphorase activity of DLD (A) as well as the glutathione reductase peroxidase activity (B). NAC vs Glutathione: Differences, Similarities And Health Benefits